A model of the interaction of the noise from a spreading subsonic jet with a 4 panel assembly is studied numerically in two dimensions. The effect of forward motion of the jet is accounted for by considering a uniform flow field superimposed on a mean jet exit profile. The jet is initially excited by a pulse-like source inserted into the flow field. The pulse triggers instabilities associated with the inviscid instability of the jet shear layer. These instabilities generate sound which in turn serves to excite the panels. We compare the sound from the jet, the responses of the panels and the resulting acoustic radiation for the static jet and the jet in forward motion. The far field acoustic radiation, the panel response and sound radiated from the panels are all computed and compared to computations of a static jet. The results demonstrate that for a jet in forward motion there is a reduction in sound in downstream directions and an increase in sound in upstream directions in agreement with experiments. Furthermore, the panel response and radiation for a jet in forward motion exhibits a downstream attenuation as compared with the static case.